Workineh Shibeshi Alemayehu

Full Name Workineh Shibeshi Alemayehu
Education attended
  • DVM,  Veterinary Medicine (Distinction), Addis Ababa University, 1998
  • MSC , Pharmacology, Addis Ababa University, 2005
  • PhD, Pharmacology,  Leipzig University, Germany, 2009


Academic Rank Assistant Professor (2005)


Working for AAU since 1998



Administrative positions held if any/ past and present  Acting Head, Department of Pharmacology and Therapeutics

Current Chair, Department of Pharmacology & Clinical Pharmacy


Awards (if any)
  • Awarded the title of Emerging Researcher, in recognition of outstanding participation in the research in the College of Health sciences, AAU, December 20, 2014
  • German Academic Exchange Service (DAAD) Scholarship for Doctoral Research and Training (2005-2009)
  • Gold Medal  of Addis Ababa University as the  best  DVM student of   the Year, 1998
Memberships of international bodies/ journals – editorial roles/ initiatives etc
  • German Society for Experimental and Clinical Pharmacology and Toxicology (2008-2009)
  • Pharmacology for Africa(PharfA)
  • Ethiopian Veterinary Association
  • Ethiopian Red cross

Reviewer for:

·         Biomed Central (BMC) Complementary and alternative medicine
·         Biomed Central (BMC) Veterinary Research
·         Drug Design, Development and Therapy
  • Time Journal of Medicinal Plant Sciences  and Pharmacology

Editorial board member for:

  • Pharmacologia
  • Austin Journal of pharmacology and Therapeutics
  • International Journal of Medicine and Medical Sciences
Address College of Health Sciences

New CHS Building

Floor number 2nd

Office room no. 5

Office tel.  + 251- 118 697103

Mobile: + 251 -927 361143

University email ID:

Alternative email ID:

Research interest/ not more than hundred words Workineh Shibeshi’s research focuses towards  understanding of beta-adrenergic receptor signaling in pulmonary diseases, clinical pharmacology, antimicrobial drug resistance , development of therapeutic leads for infectious  and non-infectious diseases, pharmaco-toxicological screening of natural products


Publications on reputable journals


  1. Ermias Mergia, Workineh Shibeshi, Getachew Terefe, Tilahun Teklehaymanot. Evaluation of In vivo Antitrypanosomal Activity of Aqueous and Methanol Leaf Extracts of Clutia abyssinica (Euphorbiaceae) against Trypanosoma congolense Field Isolate. Nat Prod Chem Res 2014, 2: 138
  2. Ermias Mergia, Workineh Shibeshi, Getachew Terefe, Tilahun Teklehaymanot. Phytochemical Screening and In Vitro Antitrypanosomal Activity of Aqueous and Methanol Leaf Extract of Verbascum sinaiticum (Scrophulariaceae) against Trypanosoma congolense Field Isolate. J Clin Exp Pathol 2014, 4: 183 : doi: 10.4172/2161-0681.1000183
  3. Miraf Mesfin, Kaleab Asres, Workineh Shibeshi. Evaluation of anxiolytic activity of the essential oil of the aerial part of Foeniculum vulgare Miller in mice. BMC Complementary and Alternative Medicine 2014, 14:310
  4. Tesfaye Gebreyohannis, Workineh Shibeshi, Kaleab Asres.Effects of Solvent Fractions of Caylusea Abyssinica (fresen.) Fisch.&mey. on Blood Glucose Levels of Normoglycemic, Glucose Loaded and Streptozotocin-induced Diabetic Rodents. Journal of Natural Remedies .Volume 14, Issue 1, January 2014


  1. Ruth Demessie, Alemayehu Mekonnen, Wondwossen Amogne, Workineh Shibeshi. Knowledge and adherence to antiretroviral therapy among adult people living with HIV/AIDS at Tikur Anbessa Specialized Hospital, Ethiopia, Int J Basic Clin Pharmacol. 2014 Apr; 3(2):1-11. Int J Basic  Clin Pharmacol. 2014 Apr; 3(2):1-11
  2. Seyfe Asrade, Workineh Shibeshi and Ephrem Engidawork .Evaluation of the reversibility and possible mechanisms of antifertility of Catha edulis F. (khat) extract following subacute administration in rodents. J. Pharm. Pharmacol, 2013; 7(40): 293-2700
  3. Mebrahtu Eyasu, Workineh Shibeshi and Mirutse Giday In vivo antimalarial activity of hydromethanolic leaf extract of Calpurnia aurea (Fabaceae) in Mice infected with chloroquine sensitive Plasmodium berghei. J. Pharm.Pharmacol. 2013, 2: 131-142
  4. Fiseha Shiferie, Workineh Shibeshi. In vivo antidiarrheal and ex-vivo spasmolytic activities of the aqueous extract of the roots of Echinops kebericho Mesfin (Asteraceae) in rodents and isolatedguinea pig ileum. International Journal of Pharmacy and Pharmacology. 2: pp. 110-116,
  5. Zerihun Kebebew, Workineh shibeshi. Evaluation of anxiolytic and sedative effects of 80% ethanolic Carica papaya L. (Caricaceae) pulp extract in mice
    Journal of Ethnopharmacology 2013 Nov 25;150(2):665-71.
  6. Teka Feyera, Getachew Terefe, Workineh Shibeshi. Phytochemical Screening and In Vitro Antitrypanosomal Activity of the Aerial Parts of Artemisia abyssinica Against Trypanosoma congolense Field Isolate. Ethiopian Pharmaceutical Journal Vol 29, No 2 (2011).
  7. Getu Abraham, Workineh Shibeshi, Fritz R. Ungemach. Identification and characterization of β-adrenergic receptors in isolated primary equine tracheal epithelial cells. Pulmonary Pharmacology & Therapeutics 24 (2011): 174-181.
  8. Abraham, g., w. shibeshi, c. zizzadoro, c. kneuer, c. ellenberger, h-a. schoon, and f. r. ungemach. “isolation, characterization and culture of primary equine bronchial epithelial cells: an in vitro model for pharmacological studies.” in journal of veterinary pharmacology and therapeutics, vol. 32, pp. 113-114. Commerce place, 350 main st, malden 02148, ma usa: wiley-blackwell publishing, inc, 2009.
  9. Workineh Shibeshi, Getu Abraham, Kneuer karsten, Christin Ellenberger,Johannes, Seegers,Heinz- Adolf Schoon, FR Ungemach (2008) Isolation and Culture of primary equine tracheal epithelial cells. In Vitro Cell Dev Biol Anim. 2008 Jul- Aug;44(7):179-84
  10. Workineh Shibeshi, Eyasu M, Asfaw D, Legesse Phytochemical,contraceptive efficacy and safety evaluations of the methanolic leaves extract of Achyranthes aspera L. in rats.
    2006, 3: 217-224
  11. Workineh Shibeshi, Eyasu Makonnen, Legesse Zerihun, Asfaw Debella. Effect of Achyranthes aspera L. On fetal abortion, uterine and pituitary weights, serum lipids and hormones. Afr Health Sci. Jun 2006; 6(2):108-112
  12. Mekonnen H, Workineh S, Bayleyegn M, Moges A, Tadele K Antimicrobial susceptibility profiles of mastitis isolates from cows in three major Ethiopian dairies. Revue Méd. Vét. 2005; 156 (7): 391-394
  13. Workineh S, Bayleyegn M, Mekonnen HM, Potgtier LND. Aetiology and prevalence of bovine mastitis in two major Ethiopian dairies. Tropical Animal Health and Production. 2002; 34: 19-25
18.      Teka Feyera,  Getachew Terefe, Workineh Shibeshi. Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against Trypanosoma congolense field isolate. MBC Complementary and Alternative Medicine (in Press)
19.      Dumessa Edessa,   Tolera Woldeyes, Workineh Shibeshi.. Comparison of effects of Isoniazid plus ART and ART only regimen on the incidence of tuberculosis and HIV progression in HIV positive patients: a retrospective cohort study at two hospitals in Addis Ababa, Ethiopia . International Journal of Basic and Clinical Pharmacology (in Press).